Cardiovascular Medicine Faculty
Kevin C. Dellsperger, M.D., Ph.D., F.A.C.C, F.A.H.A
Marie L. Vorbeck Chair- Professor and Chairman, Department of Internal Medicine
- Professor, Department of Medical Pharmacology and Physiology
Board Certification:
- Internal Medicine
- Cardiovascular Disease
Organizations:
- American Heart Association, Fellow
- American College of Cardiology, Fellow
- American College of Physicians, Fellow
- Heartland Affiliate AHA Research Committee
- American Physiological Society, Cardiovascular Section, Fellow
- Association of Professors of Medicine
- American College of Physician Executives
Medical School
Louisiana State University - Shreveport
PhD - Physiology and Biophysics
Louisiana State University - Shreveport
Residency/Chief Resident
University of Iowa Hospitals and Clinics, Iowa City, IA
Fellowship - Cardiovascular Disease
University of Iowa Hospitals and Clinics, Iowa City, IA
Honors, Awards:
- Established Investigator of the American Heart Association
- American College of Cardiology-European Society of Cardiology Young Faculty Exchange Program
- NIH National Research Service Award
- NIH Clinician Investigator Award
- President, Heartland Affiliate AHA 2001-2003.
Reserach Interests
Our laboratory evaluates mechanisms of vascular function in health and disease. Our studies currently evaluate both large conduit vascular function as well as microvascular function in collaboration with many groups throughout campus. We are focusing on the pulmonary circuit and evaluating various models of pulmonary hypertension and the influence of systemic hypertension on the pulmonary vasculature. We study how vessels respond to both constrictor and dilator stimuli and their underlying mechanisms for control. Techniques that are used in the laboratory include in vitro conduit and microvascular reactivity measurements, in vivo physiological measurements as well as biochemical and molecular measurements to elucidate signaling pathways in ex vivo tissue or isolated cells. Collaborators include Drs. Vince DeMarco, James Sowers, and M. Harold Laughlin.
Recent Publications
- Cardiovascular Disease in Women. Winn, H.N. and Dellsperger, K.C. (Eds.). Taylor and Francis Books, Ltd. London, UK. 2006.
- Junor, C. and Dellsperger, K.C. Can We Use Surrogate Vascular Beds for Evaluating Endothelial Function of the Coronary Vaculature in Patients with Cardiac Allografts? [Editorial] Am J. Physiol.: Heart Circ. Physiol. 293(1):H13-14. 2007.
- Arora, N. and Dellsperger, K.C. Heart Failure and Dialysis: New Thoughts and Trends. Adv. Periton. Dialysis 23:72-76, 2007
- Rector R.S., Warner S.O., Liu Y., Hinton P.S., Sun G.Y., Cox R.H., Stump C.S., Laughlin M.H., Dellsperger K.C., Thomas T.R. Exercise and Diet Induced Weight Loss Improves Measures of Oxidative Stress and Insulin Sensitivity in Adults with Characteristics of the Metabolic Syndrome. Am. J. Physiol.:Endo. Metabolism 293:500-506, 2007.
- Chockalingam A., Tejwani L., Aggarwal K., Dellsperger K.C. Dynamic Left Ventricular Outflow Tract Obstruction in Acute Myocardial Infarction with Shock: Cause, Effect and Coincidence. Circulation 116:e110-e113, 2007.
- Bechtold M.L., Scott S., Nelson K., Cox K.R., Dellsperger K.C., Hall L.W. Educational Quality Improvement Report: Outcomes from a Revised Morbidity and Mortality Format that Emphasized Patient Safety. Qual Saf Health Care, 16:422-427, 2007.
- DeMarco V.G., Habibi J., Whaley-Connell A.T., Schneider R.I., Heller R., Bosanquet J.P., Hayden M.R., Delcour K., Cooper S.A., Andresen B.T., Sowers J.R., and Dellsperger K.C. Oxidative Stress Contributes to Pulmonary Hypertension in the Transgenic (mRen2) 27 Ren 2 Rat. Am. J. Physiol.:Heart Circ. Physiol. 294:H2695-H2668, 2008.
