Cardiovascular Medicine Faculty
Hongmin Sun Ph.D.
Assistant Professor of MedicineHongmin Sun, Ph.D., studies the role of the blood clotting system in human disease. An underlying concept of her research program is that the blood clotting system appears to function not only to prevent bleeding, but also to contain bacterial pathogens. Using a variety of cutting-edge molecular-genetic approaches, Dr. Sun and her research team are attempting to identify new compounds that can be used to treat or prevent streptococcal infections. Streptococci are a major cause of human disease, ranging from simple infections, such as streptococcal pharyngitis (strep throat) to rheumatic fever, an important cause of human valvular heart disease. Dr. Sun’s research is funded by the National Institutes of Health.
Ph.D. Graduate School of Biomedical Sciences
University of Texas Health Science Center at HoustonHouston, TX
BS, Department of Biology
Wuhan University, ChinaRecent Publications
- Sun H, Dickinson DP, Costello J, Li WH. Isolation of cladonema pax-b genes and studies of the dna-binding properties of cnidarian pax paired domains. Mol. Biol. Evol. 2001 18:1905-18
- Sun H, Merugu S, Gu X, Kang YY, Dickinson DP, Callaerts P, Li WH Three residues largely responsible for the differences in binding specificity among paired domains. Mol. Biol. Evol. 2002 19:1490-500.
- Sun H, Yang TL, Yang A, Wang X, Ginsburg D. The murine platelet and plasma factor V pools are biosynthetically distinct and sufficient for minimal hemostasis. Blood 2003 102:2856-61.
- Sun H, Ringdahl U, Homeister JW, Fay WP, Engleberg NC, Yang AY, Rozek LS, Wang X, Sjöbring U, Ginsburg D. Plasminogen Is a Critical Host Pathogenicity Factor for Group A Streptococcal Infection. Science 2004 305:1283-6
- Sun H The Interaction between Pathogens and Host Coagulation system. Physiology 2006 21: 281-8
