Faculty Profiles
John Thyfault, Ph.D.
Assistant Professor and Health ScientistResearch Interests:
Dr. Thyfault’s primary research interest is the influence of obesity, diet, and exercise upon skeletal muscle and liver metabolism. He is also specifically interested in the regulation of insulin sensitivity in relation to diet and exercise.
Post-Doctoral Fellow - Physiology
East Carolina University-Brody School of Medicine
Greenville, North Carolina
Doctor of Exercise Physiology
The University of Kansas
Lawrence, Kansas
Master of Exercise Science
Fort Hays State University
Hays, Kansas
Selected Publications:
- Thyfault, J.P., R.S. Rector, and R.C. Noland. Metabolic inflexibility in skeletal muscle: a prelude to the CardioMetabolic Syndrome? Journal of the CardioMetabolic Syndrome. 2006 Summer;1(3):184-189
- Thyfault, J.P., M.G. Cree, J. Zwetsloot, T.R. Koves, Tapscott, E., Noland, R.C., M.G. Cree, R.R. Wolfe, D.R. Muoio and G.L. Dohm. Contraction of insulin resistant muscle normalizes insulin action in association with increased mitochondrial activity and fatty acid catabolism. Accepted in Am J of Phys – Cell Phys)
- Thyfault, J.P., R.M. Kraus, R.C. Hickner, A.W. Howell, R.R. Wolfe, and G.L. Dohm. Impaired plasma fatty acid oxidation in extremely obese women. Am J Physiol Endocrinol Metab. 2004 Dec; 287: E1076–E1081.
- Hulver, M.W., Berggren, J.R., Carper, M.J., Miyazaki, M., Ntambi, J.M., Hoffman, E.P., Thyfault, J.P., Stevens, R., G.L. DohmHoumard, J.A., and D.M. Muoio. Elevated stearoyl-CoA Desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans. Cell Metab. 2005 Oct; 2(4):251-261
- Laye, M.L., J.P. Thyfault, C.S. Stump, and F.W. Booth. Inactivity induced increase in intra-abdominal fat and adipocyte hyperplasia. (Manuscript Minor Revisisions to the Journal of Applied Physiology)
- Iglay, H.B, J.P. Thyfault, J.W. Apolzan, W.W. Campbell. Resistance training and dietary protein: Effects on glucose tolerance and contents of skeletal muscle insulin signaling proteins in older people. Accepted, American Journal of Clinical Nutrition.
Published Abstracts
- J.P. Thyfault, M.G. Cree, D. Zheng, J.J. Zwetsloot, E.B. Tapscott, T.R. Koves, R.R. Wolfe, D.M. Muoio, and G.L. Dohm. The impact of obesity, muscle contraction, and insulin on skeletal muscle lipids, a metabolomic approach. Integrative Physiology of Exercise, Sep 27-30, 2006. Indianapolis, IN.
- Stull A.J., Thyfault, J.P., Campbell W.W. The effect of acute pinitol supplementation on whole body and skeletal muscle insulin-mediated glucose metabolism. Experimental Biology 2006, San Francisco, CA, April 1-5, 2006. FASEB J 20 (4; part 1): A594, 2006.
- J.P. Thyfault, M.G. Cree, D. Zheng, J.J. Zwetsloot, E.B. Tapscott, T.R. Koves, R.R. Wolfe, D.M. Muoio, and G.L. Dohm. Contraction of insulin resistant muscle alters metabolic flux and normalizes insulin action. Keystone Meetings-Obesity and Diabetes; January 2006, Vancouver, B.C.
- Hulver, M.W., J.R. Berggren, M.J. Carper, M. Miyazaki, J.M. Ntambi, J.P. Thyfault, G.L. Dohm, J.M. Houmard, and D.M. Muoio. Elevated SCD-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans. Late breaking Abstract. Diabetes; 2005, San Diego, CA.
- Anchan, R., J.P. Thyfault, P. Shackelford, C. Isler, E. Newton, G.L. Dohm, and J. DeVente. Marked decrease in NPY concentration 24 hours after delivery in gestational diabetics and control subjects Journal of Gynecologic Investigation. 12 (2), S1, 605, 2005.
